Generically, I use this
Change directory to /etc
[root@testbed ~]# cd /etc
Now create a symbolic link (aka symlink) to the timezone e.g. Asia/Karachi (for Pakistan standard time)
[root@testbed etc]# ln -sf /usr/share/zoneinfo/Asia/Karachi localtime [root@testbed etc]# date Mon Jan 16 19:26:52 PKT 2012
Please note that the timezone is following a directory-structure so if you want EST time, you should use
[root@testbed etc]# ln -sf /usr/share/zoneinfo/EST localtime